Tisquantum—the "friendly Indian" known as Squanto in textbooks and popular accounts—is a member of the Pawtuxet settlement, located between present-day Boston and Cape Cod. Tisquantum is known for his assistance to European settlers in the early years of European colonization of North America. He speaks English, having spent time in Britain. Tisquantum works with the Pilgrims against a rival tribe, using his language skills and extensive knowledge to leverage both sides, often negotiating truces and pacts. Tisquantum falls ill and dies as the Europeans grow in power and numbers. 

Atawallpa is the son of the Wayna Inca and a ruler of the Inca Empire. Around 1520, when Wayna Inca tasks Atawallpa with conquering the peoples of the equatorial forests, Atawallpa does not succeed, and is shamed publicly. When Wayna Inca dies, his half-brother, Washkar, takes the throne. Despite this, Atawallpa mounts a bloody and costly coup, and the Inca plunge into civil war. In 1533, Washkar is captured by Spaniard Francisco Pizarro and his conquistadors. At Cajamarca, Atawallpa is double-crossed by the Spaniards, ransomed, and executed by garroting, plunging the world's greatest empire into further chaos.