George and Harold, the creators of the Dog Man comics, are in fifth grade. Their teacher is making them read classic books, like Lord of the Flies. Harold is disappointed because he thought that it was Lord of the Rings. They are inspired to write a new iteration of Dog Man.

A cop and a police dog were involved in an explosion. Their injuries left the cop’s head unsalvageable and the dog’s body unsalvageable. Doctors operated to stitch the dog’s head onto the cop’s body, creating Dog Man.

The evil cat, Petey, tried to clone himself but instead created Li’l Petey, who was nothing like him. Li’l Petey found a family with 80-HD, his robot friend, and Dog Man.

80-HD and Li’l Petey, who live with Dog Man, are repairing Dog Man’s Dogmobile. Dog Man comes home, and they have breakfast. Li’l Petey tells Dog Man that they—Li’l Petey, 80-HD, and Dog Man—are now in a new club called the Supa Buddies; they will be known as Cat Kid, The Bark Knight, and Lightning Dude.